400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / Neuronal Signaling / 5-HT Receptor & AChR / 盐酸托烷司琼
CAS No.: 105826-92-4
Synonyms: Tropisetron hydrochloride
Tropisetron HCl is a selective and competitive 5-HT3 receptor antagonist.
生物活性
靶点 | 5-HT Receptor 3 IC50:70.1±0.9nM | nAChR α7 Ki:6.9nM |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02007798 | Brain Neoplasms ... more >> Surgery Collapse << | Not Applicable | Unknown | December 2014 | China, Liaoning ... more >> Yue Yun Recruiting Shenyang, Liaoning, China, 110001 Contact: Yue Yun, Master 008613889168717 crazy_mouse0707@hotmail.com Principal Investigator: Ling Pei, Ph.D. Collapse << |
NCT02479581 | Valvular Heart Disease | Phase 2 | Completed | - | China, Hunan ... more >> Xiangya Hospital of Central South University Changsha, Hunan, China, 410078 Collapse << |
NCT02195908 | to Evaluate the Effectiveness ... more >>of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Unknown | October 2015 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
实验方案
技术信息
CAS号 | 105826-92-4 | 储存条件 |
|
|||||||
分子式 | C17H21ClN2O2 | 运输 | 蓝冰 | |||||||
分子量 | 320.81 | 别名 | Tropisetron hydrochloride | |||||||
溶解度 |
|
动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02007798 | Brain Neoplasms ... more >> Surgery Collapse << | Not Applicable | Unknown | December 2014 | China, Liaoning ... more >> Yue Yun Recruiting Shenyang, Liaoning, China, 110001 Contact: Yue Yun, Master 008613889168717 crazy_mouse0707@hotmail.com Principal Investigator: Ling Pei, Ph.D. Collapse << |
NCT02479581 | Valvular Heart Disease | Phase 2 | Completed | - | China, Hunan ... more >> Xiangya Hospital of Central South University Changsha, Hunan, China, 410078 Collapse << |
NCT02195908 | to Evaluate the Effectiveness ... more >>of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Unknown | October 2015 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT03071185 | Elective Reconstructive Surger... more >>y Pain, Post Operative Collapse << | Not Applicable | Recruiting | April 30, 2017 | China, Liaoning ... more >> School & Hospital of Stomatology, China Medical University Recruiting Shenyang, Liaoning, China, 110002 Contact: xia zhang Collapse << |
NCT01679418 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | Switzerland ... more >> Kantonsspital Liestal Liestal, Basel-Landschaft, Switzerland, 4410 Collapse << |
NCT03325816 | Small Cell Lung Cancer ... more >> Small Cell Lung Cancer Extensive Stage Collapse << | Phase 1 Phase 2 | Active, not recruiting | December 2022 | United States, District of Col... more >>umbia Georgetown Lombardi Comprehensive Cancer Center Washington, District of Columbia, United States, 20007 United States, New Jersey John Theurer Cancer Center at Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 Collapse << |
NCT02625181 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
NCT01101529 | Nausea Vomiti... more >>ng Collapse << | Phase 2 | Completed | - | Sweden ... more >> Uppsala University Hospital Uppsala, Sweden, 75185 Collapse << |
NCT01636947 | Nausea Vomiti... more >>ng Collapse << | Phase 4 | Completed | - | - |
NCT01636947 | - | - | Completed | - | - |
NCT01594749 | Chemotherapy-Induced Nausea an... more >>d Vomiting (CINV) Collapse << | Phase 3 | Completed | - | - |
NCT01594749 | - | - | Completed | - | - |
NCT03061396 | Electro-acupuncture ... more >> Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Recruiting | May 28, 2018 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT01466803 | Healthy | Phase 1 | Completed | - | Finland ... more >> Turku University Hospital Turku, Finland, 20500 Collapse << |
NCT01298193 | Breast Cancer | Phase 4 | Completed | - | Spain ... more >> Badalona, Barcelona, Spain, 08208 Alcalá de Henares, Madrid, Spain Alcorcón, Madrid, Spain, 28922 A Coruña, Spain, 15006 A Coruña, Spain, 15009 Barcelona, Spain, 08003 Barcelona, Spain, 08036 Jaén, Spain, 23007 Lleida, Spain Lugo, Spain Madrid, Spain, 28040 Valencia, Spain, 46015 Zaragoza, Spain, 50009 Collapse << |
NCT03586817 | Nausea and Vomiting, Postopera... more >>tive Collapse << | Phase 4 | Not yet recruiting | August 1, 2019 | Brazil ... more >> Hospital Federal de Bonsucesso Rio de Janeiro, Brazil, 21041-030 Collapse << |
NCT02195921 | to Evaluate the Effectiveness ... more >>of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Unknown | December 2015 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT03540537 | Quadratus Lumborum Block ... more >> Thoracic Paravertebral Block Postoperative Analgesia Hepatectomy Collapse << | Not Applicable | Recruiting | December 31, 2020 | China, Guangdong ... more >> Nanfang Hospital of Southern Medical University Recruiting Guangzhou, Guangdong, China, 510515 Contact: Tao Tao, MD 0086-18617391219 taotaomzk@smu.edu.cn Contact: Bingsha Chen, Bachelor 0086-15802031635 1550688601@qq.com Collapse << |
NCT01367808 | Pharmacokinetics and Pharmacod... more >>ynamics of Sublingual Buprenorphine Collapse << | Phase 1 | Completed | - | Finland ... more >> Department of Anaesthesiology & Intensive Care Turku, Finland, 21500 Collapse << |
NCT02478047 | Chemotherapy-induced Nausea an... more >>d Vomiting Collapse << | Not Applicable | Unknown | September 2016 | China, Tianjin ... more >> Tianjin University of TCM Not yet recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT01843868 | Lymphoma, Non-Hodgkin | Not Applicable | Unknown | December 2015 | - |
NCT00003817 | Nausea and Vomiting ... more >> Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Completed | - | United States, New Jersey ... more >> Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, New York University of Rochester Cancer Center Rochester, New York, United States, 14642 Collapse << |
NCT01226381 | Healthy Volunteers | Phase 1 | Completed | - | France ... more >> CHU Clermont-Ferrand Clermont-Ferrand, France, 63003 Collapse << |
NCT02576327 | Vomiting | Phase 4 | Unknown | December 2017 | - |
NCT03571126 | Chemotherapy-induced Nausea an... more >>d Vomiting Lung Cancer Collapse << | Phase 4 | Not yet recruiting | June 1, 2020 | - |
NCT00970450 | Analgesia | Not Applicable | Completed | - | Switzerland ... more >> University Hospital of Basel Basel, Switzerland, 4031 Collapse << |
NCT02096835 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | China, Shanghai ... more >> Department of Anesthesiology, North Institute of Huashan Hospital,Fudan University Shanghai, Shanghai, China, 201907 Collapse << |
NCT01304953 | Pain, Postoperative | Phase 4 | Completed | - | China, Hubei ... more >> Tongji Hospital Wuhan, Hubei, China, 430030 Collapse << |
NCT00889499 | Pain Chronic ... more >>Disease Collapse << | Phase 2 | Completed | - | Switzerland ... more >> Dep. of Anesthesiology and Pain Therapy, Bern University Hospital, Inselspital Bern, Switzerland, 3010 Collapse << |
NCT00435370 | Smoking Cessation ... more >> Schizophrenia Collapse << | Phase 3 | Completed | - | United States, Texas ... more >> Baylor College of Medicine - Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 China Beijing Hui-Long Guan Hospital Beijing, China Collapse << |
NCT00435370 | - | - | Completed | - | - |
NCT02096835 | - | - | Completed | - | - |
NCT02909478 | Chemotherapy-induced Nausea an... more >>d Vomiting Colorectal Cancer Collapse << | Phase 3 | Unknown | - | - |
NCT00487110 | Pain | Phase 4 | Completed | - | France ... more >> CHU Clermont-Ferrand, France, 63000 Collapse << |
NCT01895010 | Nausea Vomiti... more >>ng Metastatic Liver Cancer Collapse << | Phase 2 | Unknown | December 2014 | China, Shanghai ... more >> Shanghai Cancer Center Recruiting Shanghai, Shanghai, China, 200032 Contact: Xiaoyan Zhu, Dotral +08602164175590 ext 3625 zhuxiaoyan@fudan.edu.cn Principal Investigator: Xiaoyan Zhu, doc Collapse << |
NCT02007798 | Brain Neoplasms ... more >> Surgery Collapse << | Not Applicable | Unknown | December 2014 | China, Liaoning ... more >> Yue Yun Recruiting Shenyang, Liaoning, China, 110001 Contact: Yue Yun, Master 008613889168717 crazy_mouse0707@hotmail.com Principal Investigator: Ling Pei, Ph.D. Collapse << |
NCT02479581 | Valvular Heart Disease | Phase 2 | Completed | - | China, Hunan ... more >> Xiangya Hospital of Central South University Changsha, Hunan, China, 410078 Collapse << |
NCT02195921 | to Evaluate the Effectiveness ... more >>of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Unknown | December 2015 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT02195908 | to Evaluate the Effectiveness ... more >>of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Unknown | October 2015 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT03071185 | Elective Reconstructive Surger... more >>y Pain, Post Operative Collapse << | Not Applicable | Recruiting | April 30, 2017 | China, Liaoning ... more >> School & Hospital of Stomatology, China Medical University Recruiting Shenyang, Liaoning, China, 110002 Contact: xia zhang Collapse << |
NCT01679418 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | Switzerland ... more >> Kantonsspital Liestal Liestal, Basel-Landschaft, Switzerland, 4410 Collapse << |
NCT03325816 | Small Cell Lung Cancer ... more >> Small Cell Lung Cancer Extensive Stage Collapse << | Phase 1 Phase 2 | Active, not recruiting | December 2022 | United States, District of Col... more >>umbia Georgetown Lombardi Comprehensive Cancer Center Washington, District of Columbia, United States, 20007 United States, New Jersey John Theurer Cancer Center at Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 Collapse << |
NCT01636947 | Nausea Vomiti... more >>ng Collapse << | Phase 4 | Completed | - | - |
NCT01636947 | - | - | Completed | - | - |
NCT02625181 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
NCT03540537 | Quadratus Lumborum Block ... more >> Thoracic Paravertebral Block Postoperative Analgesia Hepatectomy Collapse << | Not Applicable | Recruiting | December 31, 2020 | China, Guangdong ... more >> Nanfang Hospital of Southern Medical University Recruiting Guangzhou, Guangdong, China, 510515 Contact: Tao Tao, MD 0086-18617391219 taotaomzk@smu.edu.cn Contact: Bingsha Chen, Bachelor 0086-15802031635 1550688601@qq.com Collapse << |
NCT01594749 | Chemotherapy-Induced Nausea an... more >>d Vomiting (CINV) Collapse << | Phase 3 | Completed | - | - |
NCT03061396 | Electro-acupuncture ... more >> Chemotherapy-induced Nausea and Vomiting Collapse << | Not Applicable | Recruiting | May 28, 2018 | China, Tianjin ... more >> Tianjin University of TCM Recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT00003817 | Nausea and Vomiting ... more >> Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Completed | - | United States, New Jersey ... more >> Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, New York University of Rochester Cancer Center Rochester, New York, United States, 14642 Collapse << |
NCT01367808 | Pharmacokinetics and Pharmacod... more >>ynamics of Sublingual Buprenorphine Collapse << | Phase 1 | Completed | - | Finland ... more >> Department of Anaesthesiology & Intensive Care Turku, Finland, 21500 Collapse << |
NCT01594749 | - | - | Completed | - | - |
NCT01101529 | Nausea Vomiti... more >>ng Collapse << | Phase 2 | Completed | - | Sweden ... more >> Uppsala University Hospital Uppsala, Sweden, 75185 Collapse << |
NCT01466803 | Healthy | Phase 1 | Completed | - | Finland ... more >> Turku University Hospital Turku, Finland, 20500 Collapse << |
NCT01298193 | Breast Cancer | Phase 4 | Completed | - | Spain ... more >> Badalona, Barcelona, Spain, 08208 Alcalá de Henares, Madrid, Spain Alcorcón, Madrid, Spain, 28922 A Coruña, Spain, 15006 A Coruña, Spain, 15009 Barcelona, Spain, 08003 Barcelona, Spain, 08036 Jaén, Spain, 23007 Lleida, Spain Lugo, Spain Madrid, Spain, 28040 Valencia, Spain, 46015 Zaragoza, Spain, 50009 Collapse << |
NCT01843868 | Lymphoma, Non-Hodgkin | Not Applicable | Unknown | December 2015 | - |
NCT02478047 | Chemotherapy-induced Nausea an... more >>d Vomiting Collapse << | Not Applicable | Unknown | September 2016 | China, Tianjin ... more >> Tianjin University of TCM Not yet recruiting Tianjin, Tianjin, China, 300193 Contact: Guo Yi, Doc 13920921016 tjutcmacupuncture@163.com Collapse << |
NCT03586817 | Nausea and Vomiting, Postopera... more >>tive Collapse << | Phase 4 | Not yet recruiting | August 1, 2019 | Brazil ... more >> Hospital Federal de Bonsucesso Rio de Janeiro, Brazil, 21041-030 Collapse << |
NCT03571126 | Chemotherapy-induced Nausea an... more >>d Vomiting Lung Cancer Collapse << | Phase 4 | Not yet recruiting | June 1, 2020 | - |
NCT01226381 | Healthy Volunteers | Phase 1 | Completed | - | France ... more >> CHU Clermont-Ferrand Clermont-Ferrand, France, 63003 Collapse << |
NCT02909478 | Chemotherapy-induced Nausea an... more >>d Vomiting Colorectal Cancer Collapse << | Phase 3 | Unknown | - | - |
NCT02096835 | - | - | Completed | - | - |
NCT01304953 | Pain, Postoperative | Phase 4 | Completed | - | China, Hubei ... more >> Tongji Hospital Wuhan, Hubei, China, 430030 Collapse << |
NCT02576327 | Vomiting | Phase 4 | Unknown | December 2017 | - |
NCT00889499 | Pain Chronic ... more >>Disease Collapse << | Phase 2 | Completed | - | Switzerland ... more >> Dep. of Anesthesiology and Pain Therapy, Bern University Hospital, Inselspital Bern, Switzerland, 3010 Collapse << |
NCT00487110 | Pain | Phase 4 | Completed | - | France ... more >> CHU Clermont-Ferrand, France, 63000 Collapse << |
NCT00435370 | - | - | Completed | - | - |
NCT02096835 | Postoperative Nausea and Vomit... more >>ing Collapse << | Not Applicable | Completed | - | China, Shanghai ... more >> Department of Anesthesiology, North Institute of Huashan Hospital,Fudan University Shanghai, Shanghai, China, 201907 Collapse << |
NCT01895010 | Nausea Vomiti... more >>ng Metastatic Liver Cancer Collapse << | Phase 2 | Unknown | December 2014 | China, Shanghai ... more >> Shanghai Cancer Center Recruiting Shanghai, Shanghai, China, 200032 Contact: Xiaoyan Zhu, Dotral +08602164175590 ext 3625 zhuxiaoyan@fudan.edu.cn Principal Investigator: Xiaoyan Zhu, doc Collapse << |
NCT00970450 | Analgesia | Not Applicable | Completed | - | Switzerland ... more >> University Hospital of Basel Basel, Switzerland, 4031 Collapse << |
NCT00435370 | Smoking Cessation ... more >> Schizophrenia Collapse << | Phase 3 | Completed | - | United States, Texas ... more >> Baylor College of Medicine - Michael E. DeBakey VA Medical Center Houston, Texas, United States, 77030 China Beijing Hui-Long Guan Hospital Beijing, China Collapse << |
靶点 | Description | IC50 |
---|---|---|
5-HT Receptor 3 | IC50:70.1±0.9nM | |
nAChR α7 | Ki:6.9nM |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网